Study on the diagnostic efficacy of lncRNA H19/miR-152-3p in vascular dementia, and its role in neuronal damage

The purpose of this study is to investigate the expression patterns and diagnostic efficacy of lncRNA H19/miR-152-3p in patients with vascular dementia (VaD). Additionally, we aim to examine its effects on neuronal damage using an oxygen-glucose deprivation/reoxygenation (OGD/R) cell model. Methods: Fifty patients with VaD admitted to Qingdao Traditional Chinese Medicine Hospital between March 2023 and April 2024 were selected as the study group. Fifty healthy individuals served as the control group. Real-time quantitative PCR technology was used to measure the expression levels of lncRNA H19 and miR-152-3p. A simple mental status examination was also conducted...